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Can Pycnogenol help? $31.99. All rights reserved. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. In a study of 76 people with allergic asthma, Pycnogenol (100 mg/day) added to conventional corticosteroid inhalers for 6 months helped 55% of them reduce inhaler use frequency and dosage. Studies on human subjects have reported few side effects - even . There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. (2004). A sitz bath, which involves sitting in warm water for 10 minutes, twice daily, is helpful to patients with anal itching, aching or burning and is known as one of the best ways to get rid of hemorrhoids fast. The study showed that many people who participated had a drop in their systolic blood pressure after taking Pycnogenol. . Pycnogenol can help control blood pressure, which helps improve overall heart health. No side effects were noted, unlike its synthetic counterpart. It had the best results when combined with compression stockings, but worked just as well alone [28]. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. Last medically reviewed on January 24, 2018. Pycnogenol treatment led to significantly better improvement in the lung function and asthma symptoms. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. They were treated with 200 mg of Pycnogenol daily or with placebo. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. The specific tree from which the bark is extracted is called a maritime pine. (14, 15). In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. Quality and active ingredients in supplements may vary widely from maker to maker. For example, Enzogenol is an extract from a pine that grows in California and Mexico (Pinus radiata) that may have cognitive-enhancing effects. Pycnogenol has been well-tolerated in most studies performed thus far. Normalization of cardiovascular risk factors in peri-menopausal women with Pycnogenol [Abstract]. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Pycnogenol treatment reduced the need for painkillers by 58% versus one percent in the placebo-treated group. You may want to start slow, taking smaller amounts, to ensure that your body works well with the OPCs found in pine bark extract. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. Cigarette smoking increases platelet aggregation. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. Diarrhea. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Ana received her MS in Pharmacy from the University of Belgrade. Enzogenol also may reduce mental fatigue and sleep problems [82]. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. It also lessened the amount of asthma medication they needed. Buy Healthy Origins Pycnogenol 100 mg (Nature's Super Antioxidant, Non-GMO, Gluten Free, Cardiovascular Support), . A Pycnogenol combination product (with l-arginine, alpha lipoic acid, B vitamins, and vitamin K2) may help protect the blood vessels and reduce high homocysteine levels, according to a trial of 25 people [39]. A study of 50 mildly infertile men found that a combination of L-arginine, L-citrulline, roburins, and Pycnogenol (Prelox R) may improve sperm quality, volume, and concentration [75]. While OPCs found in this extract are mostly known for their antioxidant-producing benefits, these amazing compounds exude antibacterial, antiviral, anticarcinogenic, anti-aging, anti-inflammatory and anti-allergic properties. You can gradually increase how much you take once you get a better idea of how your body reacts to it. High levels of both of these are considered risk factors for heart disease. The goal of this study was to evaluate if Pycnogenol could prevent deep venous thrombosis (DVT) and superficial vein thrombosis (SVT) in eight-hour flights in 196 subjects at risk of these conditions. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. This ensures that there is a healthy flow of blood to and from the heart. Disclaimer: Results are not guaranteed*** and may vary from person to person***. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. For most people, pine bark extract doesn't cause any side effects. However, this was a relatively small study, so larger ones are needed to fully understand pine bark extracts role in these findings. Help your body fight the effects of normal aging. Children who took a pine bark extract supplement for one month had healthy antioxidant levels. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. A 2015 review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity, diabetes, and high blood pressure. A combination product with Pycnogenol (Lady Prelox) improved sexual function in a clinical trial of 83 healthy postmenopausal women after 8 weeks. The dosage in most clinical studies varied between 50-360 mg/day. Abdominal pain was by far the most . According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. It also may help those on blood pressure medications to reduce their dose [32]. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. It can also stabilize mast cells, which release histamine and trigger allergic reactions. Forty-seven Japanese men with mild erectile dysfunction were given supplementation L-arginine and French maritime pine bark extract over a period of time. A study of 30 women found that Pycnogenol (75 mg/day) may reduce the skin area affected by melasma as well as lower symptoms of fatigue, constipation, body pain, and anxiety [62]. Chemistry. These wounds occur most frequently in hospitals or in those with weakened immune systems, such as after surgery. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. Align your health hacks with your genes for optimal health & cognitive function. Pycnogenol-treated patients had significant improvement in symptoms as well as a reduction in leg swelling as compared to those not receiving treatment. In a small/preliminary study of kids with asthma, pycnogenol helped improve symptoms. Pycnogenol seems to help with asthma and allergies. When pycnogenol cream was added to oral supplements in a small study of 18 people with vein ulcers, it helped ulcers heal more quickly [26]. All included participants had subclinical cognitive impairment, which looks like typical brain fog [22]. 4. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. but is for informational and educational purposes alone. A small 2017 study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. Pycnogenol and Pine Bark Extract Supplements. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. In a good-quality study, 24 adults aged 24 to 53 years old with attention deficit hyperactivity disorder (ADHD) were given Pycnogenol, placebo, or the standard drug for three weeks. (7). Its quality is specified in the United States Pharmacopeia [3]. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). Pycnogenol: A miracle component in reducing ageing and skin disorders. after four weeks of treatment, Pycnogenol-treated patients showed definite evidence of improved in small blood vessel functions and circulation as compared to those not treated. All rights reserved. View as: Grid List. Helps Treat Erectile Dysfunction. But, as you know, going for the natural approach can make a huge difference in overall health. Pycnogenol is officially extracted from the French maritime pine (Pinus pinaster), which grows in the southwest coast of France. The Benefits of DIM. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. (1, 2). Another study found this supplement can even halt progression of vision . Vinpocetine is a well-known substance in the health-hacking community with a variety of claimed health benefits. Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. We believe that the most accurate information is found directly in the scientific source. from the bark of the French maritime pine tree. A randomized placebo-controlled trial of 60 children with mild-to-moderate asthma found that those who took Pycnogenol may be able to reduce or discontinue their use of rescue inhalers more often than the placebo group [15]. Work with your pediatrician to see if there are contraindications for each child. There is currently insufficient evidence to determine what a safe and effective dose of lysine is for specific conditions. It also may help regenerate and maintain vitamin C and E levels while also potentially increasing nitric oxide levels, which may relax and protect blood vessels [1]. , Allergy: "Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. Lets begin with asthma. They were given Pycnogenolfor a period of 10 days. Blazs G, et al. Another group of men who took just l-arginine didnt improve [66]. Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. Discover what the research says about elimination diets, foods to eat, and more. Organika Pycnogenol 50mg 100 Tablets. In contrast, bleeding still occurred in the control group [61]. However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Arginine is a non-essential amino acid because most humans can make it in their bodies. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. Various brands of pycnogenol are available. In contrast, almost 20% of the participants on inhalers alone had to increase their dosage. DOI: Trebatick J, et al. According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. Moreover, Pycnogenol lowered the chemical, leukotrienes responsible for asthma attacks. In addition to OPC, grape seed extract contains linoleic acid, flavonoids and phenolic procyanidins that help protect and strengthen capillaries, blood vessels, veins and arteries, which can then improve blood circulation. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. Pycnogenol supplementation reduced skin redness from UV rays in a trial of 21 people over 8 weeks. The antibacterial activity was assessed indicating that the essential oil of pine bark, specifically the proanthocyanidins, were effective against P. aeruginosa, significantly inhibiting its growth. Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . The researchers concluded that pine bark extract may increase production of hyaluronic acid and collagen, which are both found in many popular antiaging products. Flavonoids and proanthocyanidins within these fruits can . Instead, use plain water to wipe yourself and then dry your bottom afterward. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. However, its always a good idea to start with a low dose so you can monitor how your body responds. Proper nutrition is essential for ADHD treatment. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. ", American Heart Association: Understanding Blood Pressure Readings., Iranian Journal of Public Health: "Effect of Pycnogenol Supplementation on Blood Pressure: A Systematic Review and Meta-analysis. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. There's good evidence that pycnogenol helps with eye damage caused by diabetes. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Posted on Thursday, August 14, 2014 The majority of this article is information obtained from the book "All About DIM" by Michael A. Zeligs, MD and A. Scott Connelly, MD. Dizziness. If possible, try to get pine bark extract from a local supplier, such as a health food store. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. Disease of the retina in the eye. People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. More research is needed to see how this supplement affects all of these conditions. Video: Why You Need Zinc and Where to Find It. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. . 2005 - 2023 WebMD LLC. , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. The researchers of the study propose that pycnogenol may reduce pain and cramps during retraining and rehabilitation in people with blood vessel problems [11]. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Ask your doctor for advice. For asthma in children: 1 milligram per pound of body weight given in two divided doses. Note that the numbers in parentheses (1, 2, etc.) Today's Dietitian: "Pycnogenol Supplement Offers Promise for Managing a Variety of Conditions." This condition is due to the pooling of blood in the veins of the lower legs. Our website services, content, and products are for informational purposes only. However, it's always a good idea to start with a low dose so you can monitor how your body responds. This nerve affects our balance and hearing by sending signals to the brain. Research into Pycnogenol has revealed some promising results in over 30 health conditions. Beta 1-3D Glucan is recognized by cells in the immune system, and can modify your immune system responses. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. Too much pressure signals that your heart might be working too hard. But what makes this miracle ingredient so amazing? In a clinical trial of 40 men with erectile dysfunction, 92.5% of the men on this combination regained normal erections after 3 months. Natural Factors Pycnogenol 100mg 30 Veggie Caps. If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. 5) Vein Diseases and Swelling. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. Pycnogenol seems well-tolerated for use in adults for up to 6 months. Pycnogenol in metabolic syndrome and related disorders [Abstract].