Latest: Senior Software Engineer - Front End Senior Software Engineer Senior Product Manager - Basket, Checkout and Payments UX Designer - Instore Tech. Oral use of comfrey is not recommended because of potential liver damage. Electric bowl mixer (like a KitchenAid) or a blender However, people with knee pain may be glad to try a topical preparation that could help in addition to any other recommendations made by their physician. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. Apply a small amount (not to exceed a teaspoon) topically 2-3x/day for up to 2 weeks. Quis autem velum iure reprehe nderit. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. Barna, M., Kucera, A., Hladikova, M., and Kucera, M. Randomized double-blind study: wound-healing effects of a Symphytum herb extract cream (Symphytumxuplandicum Nyman) in children. View abstract. To make the cream, combine sunflower oil, safflower oil, coconut oil, and cocoa butter in a double-boiler over low heat until completely melted. An ankle sprain can come out of nowhere and cause a lot of pain, limitations, and regret until it is healed. Regarding its antioxidant, antilipoperoxidant, antiinflammatory, and cytotoxic properties. Wien.Med Wochenschr. By Megan Nunn, PharmD Be sure to use comfrey root from a reputable source that has properly identified the species. After the consistency begins to thicken, turn the mixer up a little bit. Comfrey is a shrub that grows in parts of Europe, Asia, and North America. Additionally, because its alkaloids are absorbed through the skin, use of comfrey as a poultice should not exceed an exposure of 100 mcg/day of the alkaloids. This is not a complete list of side effects and others may occur. doi:10.1002/ptr.4612, Salehi B, Sharopov F, Boyunegmez Tumer T, et al. Comfrey is a fast-growing plant whose leaves and roots have been used historically for wound healing and other conditions. Some drugs increase how quickly the liver changes and breaks down comfrey. Aust.J Physiother. DOI:10.1211/PJ.2021.1.69803. Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. Comfrey cream Pyrrolizidine alkaloids are very toxic to the liver and are also carcinogenic (cause cancer). Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. When buying commercial brands, seek those that have had the pyrrolizidine alkaloids removed, if possible. Comfrey Definition & Meaning - Merriam-Webster Available for Android and iOS devices. Comfreycontains PAs, substances that can cause significant damage, including: Therefore, it should never be taken by mouth. COMFREY: Overview, Uses, Side Effects, Precautions - WebMD Researchers have investigated the effects of comfrey cream on several health conditions. Like any new treatment, discontinue use if any irritation occurs. Braz J Biol. Begin mixing on low. Efficacy of a comfrey root (Symphyti offic. Seal with a lid and then label with the ingredients and date. Maryland Heights, MO. Using it no more than four to six weeks a year as a general guideline would be best. It contains chemicals that are poisonous. Smith DB, Jacobson BH. Comfrey contains toxic substances that cause liver damage, cancer, and death. We are building the future of Health and Wellness Tech. Further study is needed to confirm these results. Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). 211727395. A later study of 133 peoplefound some evidence that a topical combination of comfrey extract and tannic acid led to reduced knee pain. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Copyright 1996-2023 Cerner Multum, Inc. View abstract. randomized double-blind study of 278 patients with fresh abrasions, a. topical preparation containing a 10% comfrey leaf extraction applied for 2-3 days reduced wound healing time of adults and children without side effects (Barna et al., 2012). Wound-healing effects of a symphytum herb extract cream (. J Agric.Food Chem 2001;49(8):3942-3946. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). Transfer the cooled oil and butter mixture to a standing electric mixer or blender. To use on established plants, dilute 1 part comfrey fertilizer in 15 parts water. View abstract. Tanret, I. and Duh, D. [Pharmaceutical sheet. OTHER NAME(S): Ass Ear, Black Root, Blackwort, Bruisewort, Common. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Whether youve been hiking, biking, playing, or enjoying water sports, comfrey cream can be a wonderful ally in supporting achy muscles that result from physical, summertime activities. Symphyti) bei Sprunggelenks-distorsionen. In a double-blind, randomized, placebo-controlled study involving 120 patients with acute back pain, symptoms were quickly reduced in the group using 4 grams of an ointment containing 35% comfrey root extract 3x/day for 5 days (Giannetti et al., 2010). View abstract. Efficacy and safety of topically applied Symphytum herb extract cream in the treatment of ankle distortion: Results of a randomized controlled clinical double-blind study. Potters Comfrey Oil | Holland & Barrett Shop our range of Potter's Herbals products at Holland & Barrett, including Potters Comfrey Oil. Other alternative therapies may help to ease the pain. J Pharmacopuncture 2021;24(4):196-205. Liver injury from herbal and dietary supplements. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products. Published 2021 Sep 20. doi:10.1590/1519-6984.249209, Frost R, MacPherson H, O'Meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). Medicinal use of this product has not been approved by the FDA. Nutrition C for FS and A. Wien Med Wochenschr. Kucera, M., Kalal, J., and Polesna, Z. View abstract. Comfrey flowers are bell-shaped and purple, pink, or pale yellow in color, and it has a dark taproot. To reduce the risk of side effects, never apply comfrey cream to broken skin or open wounds as it may be more highly absorbed by the body. Comfrey can also contain echimidine, pyrrolizidine alkaloids (PAs), and symphytine, which can damage the liver, are carcinogenic (cancer-causing) and may harm a fetus. 2004;11(6):470-477. Fitoterapia. how to become a school board member in florida ocean deck band schedule Although not examined in clinical trials, comfrey may possess antifungal and anticancer activity. Other uses not proven with research have included skin wounds, skin ulcers, cough, sore throat, gum disease, joint pain, diarrhea, and other conditions. Regulatory Toxicology and Pharmacology, 83, 1-4. https://doi.org/10.1016/j.yrtph.2016.11.015. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. 2012;20(11):1209-16. doi:10.1016/j.joca.2012.07.019, Zago LR, Prado K, Benedito VL, Pereira MM. Comfrey is a flowering shrub that grows in Europe, Asia and, now, North America. Do not use comfrey with very young children or during pregnancy or lactation. What is niacinamide? hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial. WebMD does not provide medical advice, diagnosis or treatment. However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. Simply massage into the skin as required. Select a condition to view a list of vitamins. 2013;21(6):724-745. doi:10.1016/j.ctim.2013.09.009. A review of 26 clinical trials concluded that mild skin reactions were the most common side effects of comfrey creams used in the studies. Skin patch test before use, especially if you have sensitive skin, and never use on a deep wound. Comfrey is considered likely unsafe to use if you are nursing a baby. Natural Standard. Because of the risk of liver toxicity, comfrey cream shouldn't be used with other medicines that may also cause liver damage. (2004). Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. 2014;20(4):347-55. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. 6 Healing Benefits of Comfrey. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. In a small study with 30 subjects, lower back pain from exercise was reduced with an ointment containing comfrey. 2012;26(10):14411448. One group used a cream with comfrey root fluid extract on the ankle while the others received a placebo. View abstract. reduce lower back pain (Stam et al., 2001). Retrieved from, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295. Please read the Topical Use Safety section of this article (above) before using. Choose organically grown comfrey when possible. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Here's a look at research on comfrey cream for back pain, osteoarthritis, and ankle sprains. The study involved 43 patients with knee osteoarthritis and a six-week treatment period. We comply with the HONcode standard for trustworthy health information. about an hour two nites. Stickel F, Seitz HK. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. Food and Drug Administration. Comfrey may also be used for purposes not listed in this product guide. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Two interesting studies found that a topical application of a product containing comfrey root extract helped with knee pain and stiffness. Call your doctor if the condition you are treating with comfrey does not improve, or if it gets worse while using this product. . This could change the effects and side effects of comfrey. This recipe is contraindicated for small children and those with certain medical conditions. New South Wales Health, Australia. If you're considering using the cream, consult your healthcare provider first. The Pharmaceutical Journal, PJ, December 2007. However, comfrey can also contain toxic substances called pyrrolizidine alkaloids that cause liver damage, cancer, and death. Save the remaining liquid alcohol portion. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Researchers have found it does seem to reduce pain in some conditions, including back pain, osteoarthritis, and ankle sprains. Do not use more of this product than is recommended on the label. This is memorable if you have worked with it, and some use this quality to remember comfreys centuries-long useapplying comfrey over bones, bruises, sprains, and minor wounds with the intention to support mending! View abstract. Limited trials have evaluated the effectiveness of alkaloid-free preparations for external use; however, these studies did not examine how much liver damage occurred in patients. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Scoop the finished comfrey cream into sanitized glass jars. These have a lower risk of serious side effects like liver damage. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Efficacy and tolerance of a comfrey root extract (Extr. A symptomatic treatment of minor sprains and bruises. View abstract. Efficacy and tolerance of a comfrey root extract (Extr. Comfrey shouldn't be used in any form during pregnancy or nursing due to the risk of liver damage to infants. 12 drops juniper berry (Juniperus communis) essential oil 2010;73(2):97-100. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Using a combination product makes it challenging to know how much of the beneficial effect came from comfrey alone. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Discard after a year or according to labeling. Phytomedicine 2005;12(10):707-714. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). Rad. The first European settlers of America considered comfrey so indispensable, they carried it on their journey across the Atlantic in the 1600s.2. Cbd Oil In Holland And Barrett. Some of these components are thought to speed up wound healing by stimulating new cell growth. Commercial comfrey sale and distribution is restricted in Germany and Canada because of its substantial toxicity. Giannetti, B. M., Staiger, C., Bulitta, M., and Predel, H. G. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial. Comfrey contains chemicals called. 2017;83:1-4. BMJ Case Rep. 2016. It is not certain whether comfrey is effective in treating any medical condition. After the tincture is made, then you can whip up the fabulous joint and muscle cream! The way that they work is by blocking small blood vessels in the liver. Vithayathil MK, Edwards M. Comfrey herbal remedy causing second-degree heart block: do not be outfoxed by digitalis. Megan Nunn, PharmD, is a community pharmacist in Tennessee with over twelve years of experience in medication counseling and immunization. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. Comfrey is avoided on cuts or puncture wounds for this reason. Comfrey - The Lost Herbs Comfrey Oil: Benefits, Uses & Risks | Holland & Barrett Resuscitation 2008;76(3):323-324. Looks like you may need to upgrade your browser We're sorry, we no longer support the web browser that you are using View abstract. View abstract. Huxtable RJ, Awang DV. Call your doctor for medical advice about side effects. Barthomeuf, C. M., Debiton, E., Barbakadze, V. V., and Kemertelidze, E. P. Evaluation of the dietetic and therapeutic potential of a high molecular weight hydroxycinnamate-derived polymer from Symphytum asperum Lepech. The combination of Vitamin E, Wheat Germ oil and Rice Bran oil makes this cream perfect for your daily hydration needs. Using different formulations together increases the risk of an overdose. It's found in Europe, Asia, and North America. Understand comfreys contraindications before using it. Do not use different forms (tablets, liquid, tincture, teas, etc) of comfrey at the same time without medical advice. Rad. Comfrey has long been used in folk traditions for bruising and abrasions. Registered office: Samuel Ryder House, Barling Way, Eliot Park, Nuneaton, CV10 7RH, UK. Amendments to the poison list. Terry Naturally Traumaplant Comfrey Cream - amazon.com View abstract. View abstract. Do not use this product without medical advice if you are pregnant. View abstract. , meaning to grow together. Definitely do not use during pregnancy or nursing, with infants, and if you have liver or kidney disease. These include allantoin, rosmarinic acid, and others. Phytomedicine. Mosby Elsevier. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. *PR sample. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. A handbook for practice on a scientific basis. Available for Android and iOS devices. Toxicol Lett 2005;155:411-20. The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. Hepatology. randomized, placebo-controlled, double-blind, multi-clinical trial. Sowa I, Paduch R, Strzemski M, et al. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). 4.3 4.3 out of 5 stars (225) $19.95 $ 19. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. D'Anchise, R., Bulitta, M., and Giannetti, B. Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). Double boiler Aust.Fam.Physician 2008;37(4):235-236. View abstract. Wien.Med.Wochenschr. The plant leaves have a lower concentration of PAs than the roots. The following applications have been used in research: Using large amounts of comfrey cream or using it for extended periods of time increases the risk of side effects like liver toxicity. However, not a rate considered harmful for those with healthy livers.10,11, Masters Degree in Toxicology and BSc Hons in Medical Biochemistry. Ulbricht, C. (2010). You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. In a randomized, controlled, double-blind study with 203 patients, applications of a 10% comfrey cream were well tolerated, reduced swelling and pain, and improved mobility (Kucera et al., 2004). Z Phytotherapie 2000;21:127-134. What Happens If I Use Too Much Comfrey Cream? After eight days, the group that used the cream had significantly less pain than those who had the placebo. (2001). The roots and leaves of the comfrey plant have medicinal properties. 2013;27(6):811-7. HOLLAND & BARRETT PRO VITAMIN E DAY CREAM 50ML This Vitamin E day cream works with your skin daily to hydrate and protect your skin. Some medications can also harm the liver. comfrey cream holland and barrettfeathered friend questions and answers. Avoid taking comfrey orally (by mouth). comfrey cream holland and barrett - creditsolutionexperts.com Make sure to always buy comfrey. There is no daily recommended allowance for comfrey, sold in creams, ointments, gels, and salves. J Chiropr Med. When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. Modern science suggests that the ancients were correct in believing comfrey helps to heal woundsand relieve pain.3,4 In this article, well explain where comfrey comes from, comfrey oils remarkable health benefits and how to use it at home. Avoid using comfrey together with other herbal/health supplements that can also harm the liver. Comfrey root extracts have been used by herbalists and in folk traditions for centuries to soothe aches and pains. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. 2016 Jan;41(2):116-33. doi:10.1097/01.brs.0000249525.70011.fe. When the root is boiled in water, it forms a sticky, glue-like paste. Dosage: How Much Comfrey Cream Should I Use? Comfrey has been used in alternative medicine as a possibly effective aid in treating back pain, osteoarthritis, or tenderness and swelling caused by a sprain injury. Comfrey contains chemicals that cause serious liver damage when taken by mouth. Do not give any herbal/health supplement to a child without medical advice. Comfrey is often sold as an herbal supplement. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. Other drugs may interact with comfrey, including prescription and over-the-counter medicines, vitamins, and herbal products. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). If you choose to use comfrey, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Jurcu, R., & Jurcu, I. Influence of moderate physical exertion on subacute low back pain, after Symphytum officinale ointment treatment. 2007;57(11):712-716. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. This site uses cookies to improve your experience. 2012;101(4):211-216. 2012;(1):41-42. Verywell Health's content is for informational and educational purposes only. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. Which part of the comfrey plant has the lowest level of pyrrolizidine alkaloids (PAs)? Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. Consult your healthcare provider before using. Satisfaction. What are the benefits of using it? The chemicals contained in comfrey may cause birth defects. We currently have no information for COMFREY overview. When considering the use of herbal supplements, seek the advice of your doctor. You may report side effects to FDA at 1-800-FDA-1088. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. (2001). The Herbal Academy supports trusted organizations with the use of affiliate links. Please review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications. Copyright Holland & Barrett Limited 2023. Public Health Nutr 2000;3:501-8. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. cup organic sunflower oil of India and by a State Level Environment Impact Assessment Authority constituted by Government of India on the recommendations made . You and your healthcare provider should weigh the pros and cons and use it only under their supervision. Add comfy to Vaseline . The recipe makes about 5 cups of whipped creamy lotion. COMFREY Reviews and User Ratings: Effectiveness, Ease of Use - WebMD Comfrey Cream Recipe for Achy Joints and Muscles - Herbal Academy Avila C, Breakspear I, Hawrelak J, Salmond S, Evans S. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietician, pharmacist, or healthcare provider. Amazon.com: Comfrey Cream What Are the Side Effects of Comfrey Cream? 12 drops black pepper (Piper nigrum) essential oil Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Comfrey [Online article]. Our associates are qualified to advise, visit us online or in store for unparalleled advice. Also, avoid use for more than two weeks or excessive concentrations containing more than 100 mcg of pyrrolizidine alkaloids (Wichtl, 2004 & Ulbricht, 2010). 2019;24(12):2272. doi:10.3390/molecules24122272, Staiger, Christine. Our Two Pennies Worth. Experts suggest not using comfrey cream for longer than ten days in a row. Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. These side effects may be common or severe. (2013). This leads to cirrhosis and eventually liver failure. This site uses cookies to improve your experience. The Herbal Academy neither endorses them nor is in any way responsible for their content. Comfrey Uses, Side Effects & Warnings - Drugs.com